Coding

Part:BBa_K2804015:Design

Designed by: Byron Francisco Mosquera   Group: iGEM18_Ecuador   (2018-10-14)


CBD cipA fused to BMP2


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

BMP2 was fused to the C-terminus of CBD cipA because the osteogenic activity of the C-terminal domain of BMP2.


Source

Fusion Assembly

References

Schmoekel, H.G., Weber, F.E., Schense, J.C., Grätz, K.W., Schawalder, P. & Hubbell, J.A. (2005). Bone repair with a form of BMP-2 engineered for incorporation into fibrin cell ingrowth matrices. Biotechnology and Bioengineering